I found the following very interesting (taken off another blog I read regularly):
Jean-Dominique Bauby wrote a book called the Diving Bell and the Butterfly after suffering a stroke that left him totally paralyzed, save his blinking left eye (which he used to communicate words to an assistant). Going inside the mind of someone literally frozen is a deep experience. Add to it that Bauby is an extremely talented writer and you have something truly remarkable.
An interesting point & quote:
* After his stroke, Bauby's favorite letters from friends were not those which discussed the meaning of life but those which captured the small events which "punctuate the passage of time: roses picked at dusk, the laziness of a rainy Sunday, a child crying himself to sleep." Interestingly, the letters about deep philosophical issues were from the friends he knew the least well.